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Volume:1, Issue:1- Research Article

Endocarditis caused by Staphylococcus aureus: A Rare Case of Aortic Valve Perforation

Sergio Fasullo*, Giorgio Maringhini, Vincenzo Bucca, Gianmauro Rinciari, Giovanni Lipari, Filippo Ganci, Fernanda Pipitone, Sebastiano Scalzo, Vito Pinto, Nicola La Manna, Nicola Morabito, Carlo Li Castri, Stefania Davi, and Vincenzo Argano


We report a case of acute endocarditis with aortic valve destruction caused by Methicillin-resistant Staphylococcus aureus in a 60 year old woman in healthy valve after dental extraction without bacterial prophylaxis. S. aureus is an aggressive pathogen and bacteremia with this organism can infect healthy heart valves. Neurological complications of infective endocarditis, particularly embolic events, tend to be higher with this organism. S. aureus typically causes acute endocarditis and progresses to death within weeks if left untreated.

Methicillin-resistant Staphylococcus aureus (MRSA) is a gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus. MRSA is any strain of S. aureus that has developed multiple drug resistance to betalactam antibiotics. During the hospitalization there was also the sudden appearance of hemolytic anemia and thrombocytopenia, fever and neurological dysfunction. The patient received intensive treatment with antibiotics(gentamicin and daptomycin). Given the slow and ineffective clinical response, it has undergone the success of aortic valve replacement.

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